CD54 / ICAM-1 Antibody - With BSA and Azide, Clone: [F4-31C2], Mouse, Monoclonal
Artikelnummer:
ABT-AH11485-U0020
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| Artikelname: | CD54 / ICAM-1 Antibody - With BSA and Azide, Clone: [F4-31C2], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH11485-U0020 |
| Hersteller Artikelnummer: | AH11485-U0020 |
| Alternativnummer: | ABT-AH11485-U0020-20UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, CD54, ICAM1 |
| Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors. |
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