CD45 (8C1) Mouse mAb, Clone: [8C1-9B8-2H1], Monoclonal

Artikelnummer: ABT-AP53505
Artikelname: CD45 (8C1) Mouse mAb, Clone: [8C1-9B8-2H1], Monoclonal
Artikelnummer: ABT-AP53505
Hersteller Artikelnummer: AP53505
Alternativnummer: ABT-AP53505-100UL
Hersteller: Abcepta
Wirt: Mouse
Kategorie: Antikörper
Applikation: IF, IHC-P, WB
Alternative Synonym: GP180, L CA, CD45 antigen
Swiss-Prot Acc.P06800.Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.
Klonalität: Monoclonal
Klon-Bezeichnung: [8C1-9B8-2H1]
NCBI: 19264
UniProt: P06800