CD45 (8C1) Mouse mAb, Clone: [8C1-9B8-2H1], Monoclonal
Catalog Number:
ABT-AP53505
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| Article Name: | CD45 (8C1) Mouse mAb, Clone: [8C1-9B8-2H1], Monoclonal |
| Biozol Catalog Number: | ABT-AP53505 |
| Supplier Catalog Number: | AP53505 |
| Alternative Catalog Number: | ABT-AP53505-100UL |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | IF, IHC-P, WB |
| Alternative Names: | GP180, L CA, CD45 antigen |
| Swiss-Prot Acc.P06800.Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity. |
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