HERC5 Antibody - N-terminal region
Artikelnummer:
ASB-ARP43212_P050
- Bilder (3)
| Artikelname: | HERC5 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP43212_P050 |
| Hersteller Artikelnummer: | ARP43212_P050 |
| Alternativnummer: | ASB-ARP43212_P050-25UL,ASB-ARP43212_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human HERC5 |
| Alternative Synonym: | CEB1, CEBP1 |
| HERC5 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. |



