HERC5 Antibody - N-terminal region

Catalog Number: ASB-ARP43212_P050
Article Name: HERC5 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP43212_P050
Supplier Catalog Number: ARP43212_P050
Alternative Catalog Number: ASB-ARP43212_P050-25UL,ASB-ARP43212_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Human
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HERC5
Alternative Names: CEB1, CEBP1
HERC5 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 117kDa
NCBI: 51191
UniProt: Q9UII4
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-HERC5 antibody
Catalog Number: ARP43212
Formalin Fixed Paraffin Embedded Tissue: Human Testis
Primary antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20x
Exposure Time: 0.5-2.0sec
WB Suggested Anti-HERC5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HT1080 cell lysate
HERC5 antibody - N-terminal region (ARP43212_P050) in Human HT1080 using Western Blot