HERC5 Antibody - N-terminal region
Catalog Number:
ASB-ARP43212_P050
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| Article Name: | HERC5 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP43212_P050 |
| Supplier Catalog Number: | ARP43212_P050 |
| Alternative Catalog Number: | ASB-ARP43212_P050-25UL,ASB-ARP43212_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human HERC5 |
| Alternative Names: | CEB1, CEBP1 |
| HERC5 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. |



