RASGRP1 Antibody - C-terminal region
Artikelnummer:
ASB-ARP63788_P050
- Bilder (3)
| Artikelname: | RASGRP1 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP63788_P050 |
| Hersteller Artikelnummer: | ARP63788_P050 |
| Alternativnummer: | ASB-ARP63788_P050-25UL,ASB-ARP63788_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Alternative Synonym: | IMD64, RASGRP, CALDAG-GEFI, CALDAG-GEFII |
| This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). |
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WB Suggested Anti-RASGRP1 Antibody Titration: 1.0 ug/ml Positive Control: Jurkat Whole CellRASGRP1 is supported by BioGPS gene expression data to be expressed in Jurkat |
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Host: Rabbit Target Name: RASGRP1 Sample Tissue: Human HCT116 Whole Cell Antibody Dilution: 3ug/ml |
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RASGRP1 antibody - C-terminal region (ARP63788_P050) in Human Jurkat using Western Blot |
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