RASGRP1 Antibody - C-terminal region

Catalog Number: ASB-ARP63788_P050
Article Name: RASGRP1 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP63788_P050
Supplier Catalog Number: ARP63788_P050
Alternative Catalog Number: ASB-ARP63788_P050-25UL,ASB-ARP63788_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Alternative Names: IMD64, RASGRP, CALDAG-GEFI, CALDAG-GEFII
This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 90kDa
NCBI: 10125
UniProt: O95267
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-RASGRP1 Antibody
Titration: 1.0 ug/ml
Positive Control: Jurkat Whole CellRASGRP1 is supported by BioGPS gene expression data to be expressed in Jurkat
Host: Rabbit
Target Name: RASGRP1
Sample Tissue: Human HCT116 Whole Cell
Antibody Dilution: 3ug/ml
RASGRP1 antibody - C-terminal region (ARP63788_P050) in Human Jurkat using Western Blot