PICALM Antibody - C-terminal region

Artikelnummer: ASB-ARP63958_P050
Artikelname: PICALM Antibody - C-terminal region
Artikelnummer: ASB-ARP63958_P050
Hersteller Artikelnummer: ARP63958_P050
Alternativnummer: ASB-ARP63958_P050-25UL,ASB-ARP63958_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Alternative Synonym: LAP, CALM, CLTH
This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10,11)(p13,q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 60kDa
NCBI: 8301
UniProt: E9PN05
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-PICALM Antibody
Catalog Number: ARP63958_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-PICALM Antibody
Titration: 1.0 ug/ml
Positive Control: Jurkat Whole Cell
PICALM antibody - C-terminal region (ARP63958_P050) in Human Jurkat using Western Blot