PICALM Antibody - C-terminal region

Catalog Number: ASB-ARP63958_P050
Article Name: PICALM Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP63958_P050
Supplier Catalog Number: ARP63958_P050
Alternative Catalog Number: ASB-ARP63958_P050-25UL,ASB-ARP63958_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Alternative Names: LAP, CALM, CLTH
This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10,11)(p13,q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 60kDa
NCBI: 8301
UniProt: E9PN05
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-PICALM Antibody
Catalog Number: ARP63958_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-PICALM Antibody
Titration: 1.0 ug/ml
Positive Control: Jurkat Whole Cell
PICALM antibody - C-terminal region (ARP63958_P050) in Human Jurkat using Western Blot