TPMT Antibody
Artikelnummer:
ASB-OAAL00341
- Bilder (3)
| Artikelname: | TPMT Antibody |
| Artikelnummer: | ASB-OAAL00341 |
| Hersteller Artikelnummer: | OAAL00341 |
| Alternativnummer: | ASB-OAAL00341-100UG |
| Hersteller: | Aviva |
| Wirt: | Mouse |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IF, WB |
| Spezies Reaktivität: | Human, Mouse |
| Immunogen: | TPMT (AAH05339, 1 a.a. ~ 245 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Alternative Synonym: | S-adenosyl-L-methionine:thiopurine S-methyltransferase,thiopurine S-methyltransferase,TPMTD. |
| This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq |
| Klonalität: | Monoclonal |
| Klon-Bezeichnung: | [1D4] |
| NCBI: | 7172 |
| Formulierung: | Liquid |
|
|
Detection limit for recombinant GST tagged TPMT is approximately 1ng/ml as a capture antibody. |
|
|
Immunofluorescence of monoclonal antibody to TPMT on HeLa cell. [antibody concentration 10 ug/ml] |
|
|
Western Blot analysis of TPMT expression in transfected 293T |
Produktgarantie und fachkundiger Support
