TPMT Antibody
Catalog Number:
ASB-OAAL00341
- Images (3)
| Article Name: | TPMT Antibody |
| Biozol Catalog Number: | ASB-OAAL00341 |
| Supplier Catalog Number: | OAAL00341 |
| Alternative Catalog Number: | ASB-OAAL00341-100UG |
| Manufacturer: | Aviva |
| Host: | Mouse |
| Category: | Proteine/Peptide |
| Application: | ELISA, IF, WB |
| Species Reactivity: | Human, Mouse |
| Immunogen: | TPMT (AAH05339, 1 a.a. ~ 245 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Alternative Names: | S-adenosyl-L-methionine:thiopurine S-methyltransferase,thiopurine S-methyltransferase,TPMTD. |
| This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq |
| Clonality: | Monoclonal |
| Clone Designation: | [1D4] |
| NCBI: | 7172 |
| Form: | Liquid |
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Detection limit for recombinant GST tagged TPMT is approximately 1ng/ml as a capture antibody. |
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Immunofluorescence of monoclonal antibody to TPMT on HeLa cell. [antibody concentration 10 ug/ml] |
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Western Blot analysis of TPMT expression in transfected 293T |
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