RANBP3 Antibody
Artikelnummer:
ASB-OACA08985
- Bilder (3)
| Artikelname: | RANBP3 Antibody |
| Artikelnummer: | ASB-OACA08985 |
| Hersteller Artikelnummer: | OACA08985 |
| Alternativnummer: | ASB-OACA08985-100UL,ASB-OACA08985-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC, WB |
| Spezies Reaktivität: | Human, Mouse |
| Immunogen: | Recombinant Human Ran-binding protein 3 protein (1-250AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | epididymis secretory sperm binding protein,ran-binding protein 3. |
| Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export. |
| Klonalität: | Polyclonal |
| NCBI: | 8498 |
| Formulierung: | Liquid |
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Immunohistochemistry of paraffin-embedded human pancreatic cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100 |
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Western blot All lanes: RANBP3 antibody at 6.4ug/ml Lane 1: Mouse brain tissue |
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