RANBP3 Antibody
Catalog Number:
ASB-OACA08985
- Images (3)
| Article Name: | RANBP3 Antibody |
| Biozol Catalog Number: | ASB-OACA08985 |
| Supplier Catalog Number: | OACA08985 |
| Alternative Catalog Number: | ASB-OACA08985-100UL,ASB-OACA08985-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Ran-binding protein 3 protein (1-250AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | epididymis secretory sperm binding protein,ran-binding protein 3. |
| Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export. |
| Clonality: | Polyclonal |
| NCBI: | 8498 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human pancreatic cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100 |
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Western blot All lanes: RANBP3 antibody at 6.4ug/ml Lane 1: Mouse brain tissue |
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