MMACHC Antibody

Artikelnummer: ASB-OACA09247
Artikelname: MMACHC Antibody
Artikelnummer: ASB-OACA09247
Hersteller Artikelnummer: OACA09247
Alternativnummer: ASB-OACA09247-100UL,ASB-OACA09247-50UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: ELISA, IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant Human Methylmalonic aciduria and homocystinuria type C protein (63-282AA)
Konjugation: Unconjugated
Alternative Synonym: alkylcobalamin:glutathione S-alkyltransferase,cblC,cyanocobalamin reductase (cyanide-eliminating),cyanocobalamin reductase / alkylcobalamin dealkylase,methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria,methylmalonic aciduria and homocystinuria type C protein.
Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using FAD or FMN as cofactor and NADPH as cosubstrate (PubMed:19700356, PubMed:21697092, PubMed:22642810). Can also catalyze the glutathione-dependent reductive demethylation of methylcobalamin, and, with much lower efficiency, the glutathione-dependent reductive demethylation of adenosylcobalamin (PubMed:19801555, PubMed:22642810, PubMed:25809485). Under anaerobic conditions cob(I)alamin is the first product, it is highly reactive and is converted to aquocob(II)alamin in the presence of oxygen (PubMed:19801555). Binds cyanocobalamin, adenosylcobalamin, methylcobalamin and other, related vitamin B12 derivatives (PubMed:21071249).
Klonalität: Polyclonal
NCBI: 25974
Formulierung: Liquid
Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
Western blot
All lanes: MMACHC antibody at 5.16 ug/ml
Lane 1: HepG-2 wh