MMACHC Antibody
Catalog Number:
ASB-OACA09247
- Images (3)
| Article Name: | MMACHC Antibody |
| Biozol Catalog Number: | ASB-OACA09247 |
| Supplier Catalog Number: | OACA09247 |
| Alternative Catalog Number: | ASB-OACA09247-100UL,ASB-OACA09247-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Methylmalonic aciduria and homocystinuria type C protein (63-282AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | alkylcobalamin:glutathione S-alkyltransferase,cblC,cyanocobalamin reductase (cyanide-eliminating),cyanocobalamin reductase / alkylcobalamin dealkylase,methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria,methylmalonic aciduria and homocystinuria type C protein. |
| Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using FAD or FMN as cofactor and NADPH as cosubstrate (PubMed:19700356, PubMed:21697092, PubMed:22642810). Can also catalyze the glutathione-dependent reductive demethylation of methylcobalamin, and, with much lower efficiency, the glutathione-dependent reductive demethylation of adenosylcobalamin (PubMed:19801555, PubMed:22642810, PubMed:25809485). Under anaerobic conditions cob(I)alamin is the first product, it is highly reactive and is converted to aquocob(II)alamin in the presence of oxygen (PubMed:19801555). Binds cyanocobalamin, adenosylcobalamin, methylcobalamin and other, related vitamin B12 derivatives (PubMed:21071249). |
| Clonality: | Polyclonal |
| NCBI: | 25974 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution of 1:100 |
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Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100 |
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Western blot All lanes: MMACHC antibody at 5.16 ug/ml Lane 1: HepG-2 wh |
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