DK419 is a potent, orally bioavailable small molecule inhibitor of the Wnt/beta-catenin pathway (IC50 = 0.19 µM). It downregulates key oncogenic targets including Axin2, beta-catenin, c-Myc, Cyclin D1, and Survivin while activating pAMPK. This inhibitor is a valuable research tool for studying Wnt-driven cancers in both cellular and animal models.
Molekulargewicht:
407.7
Reinheit:
99.63% (May vary between batches)
CAS Nummer:
[2102672-22-8]
Formel:
C16H8ClF6N3O
Target-Kategorie:
CDK,c-Myc,AMPK,Survivin,Wnt/beta-catenin
Anwendungsbeschreibung:
Solubility: DMSO:< 1 mg/mL (insoluble or slightly soluble)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
