TSLP Antibody, Unconjugated, Monoclonal
Artikelnummer:
BYT-ORB1805495
- Bilder (6)
| Artikelname: | TSLP Antibody, Unconjugated, Monoclonal |
| Artikelnummer: | BYT-ORB1805495 |
| Hersteller Artikelnummer: | orb1805495 |
| Alternativnummer: | BYT-ORB1805495-1,BYT-ORB1805495-100 |
| Hersteller: | Biorbyt |
| Kategorie: | Antikörper |
| Applikation: | ELISA, FA, FACS, In vivo |
| Spezies Reaktivität: | Human, Monkey |
| Konjugation: | Unconjugated |
| Anti-TSLP Reference Antibody is expressed from CHO. The heavy chain type is huIgG2, and the light chain type is hulambda. It has a predicted MW of 145.5 kDa. |
| Klonalität: | Monoclonal |
| Konzentration: | Batch dependent |
| Molekulargewicht: | 144.6 kDa |
| UniProt: | Q969D9 |
| Puffer: | 100 mM Proline/Acetic acid 20mM Arginine pH 5.0 |
| Reinheit: | >95% |
| Target-Kategorie: | TSLP |
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Anti-TSLP Reference Antibody (tezepelumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%. |
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The purity of Anti-TSLP Reference Antibody (tezepelumab)is more than 98.64% ,determined by SEC-HPLC. |
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Immobilized human TSLP His at 2 µg/mL can bind Anti-TSLP Reference Antibody (tezepelumab),EC50=0.0518µg/mL. |
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orb1805495 |
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Anti-TSLP Reference Antibody (tezepelumab)-induced FACS Blocking activity was evaluated using TSLPR/IL7R-CHO-K. The IC50 was approximately 0.0802 µg/mL. |
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Tezepelumab reduced levels of IL13 in BALF of OVA asthma model on B-hTSLP/hTSLPR mice. The result showed significant IL13 inhibition effects at 15 mpk. |
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