TREM1/CD354 Antibody, Unconjugated, Monoclonal

Artikelnummer: BYT-ORB1805967
Artikelname: TREM1/CD354 Antibody, Unconjugated, Monoclonal
Artikelnummer: BYT-ORB1805967
Hersteller Artikelnummer: orb1805967
Alternativnummer: BYT-ORB1805967-1,BYT-ORB1805967-100
Hersteller: Biorbyt
Kategorie: Antikörper
Applikation: ELISA, FA, FACS, In vivo
Spezies Reaktivität: Human
Konjugation: Unconjugated
Anti-TREM1 / CD354 Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
Klonalität: Monoclonal
Konzentration: Batch dependent
Molekulargewicht: 143.66 kDa
UniProt: Q9NP99
Puffer: 100 mM Proline/Acetic acid 20mM Arginine pH 5.0
Reinheit: >95%
Target-Kategorie: TREM1 / CD354
Anti-TREM1 / CD354 Reference Antibody (PY159) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-TREM1 / CD354 Reference Antibody (PY159)is more than 95% ,determined by SEC-HPLC.
Immobilized human TREM1 His at 2 µg/mL can bind Anti-TREM1 / CD354 Reference Antibody (PY159),EC50=0.00645µg/mL.
Human TREM1 HEK293 cells were stained with Anti-TREM1 / CD354 Reference Antibody (PY159) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC275=0.7744nM.
The endocytosis ratio PY159 by hu-TREM1-HEK293 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 80% at antibody concentration of 0.3 nM.
Anti-TREM1 Reference Antibody (PY159) Activation was evaluated using PBMC. The max induction fold was approximately 3.16.