TREM1/CD354 Antibody, Unconjugated, Monoclonal

Catalog Number: BYT-ORB1805967
Article Name: TREM1/CD354 Antibody, Unconjugated, Monoclonal
Biozol Catalog Number: BYT-ORB1805967
Supplier Catalog Number: orb1805967
Alternative Catalog Number: BYT-ORB1805967-1,BYT-ORB1805967-100
Manufacturer: Biorbyt
Category: Antikörper
Application: ELISA, FA, FACS, In vivo
Species Reactivity: Human
Conjugation: Unconjugated
Anti-TREM1 / CD354 Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
Clonality: Monoclonal
Concentration: Batch dependent
Molecular Weight: 143.66 kDa
UniProt: Q9NP99
Buffer: 100 mM Proline/Acetic acid 20mM Arginine pH 5.0
Purity: >95%
Target: TREM1 / CD354
Anti-TREM1 / CD354 Reference Antibody (PY159) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-TREM1 / CD354 Reference Antibody (PY159)is more than 95% ,determined by SEC-HPLC.
Immobilized human TREM1 His at 2 µg/mL can bind Anti-TREM1 / CD354 Reference Antibody (PY159),EC50=0.00645µg/mL.
Human TREM1 HEK293 cells were stained with Anti-TREM1 / CD354 Reference Antibody (PY159) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC275=0.7744nM.
The endocytosis ratio PY159 by hu-TREM1-HEK293 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 80% at antibody concentration of 0.3 nM.
Anti-TREM1 Reference Antibody (PY159) Activation was evaluated using PBMC. The max induction fold was approximately 3.16.