CDH6/K-Cadherin Antibody, Unconjugated, Monoclonal
Artikelnummer:
BYT-ORB1806273
- Bilder (6)
| Artikelname: | CDH6/K-Cadherin Antibody, Unconjugated, Monoclonal |
| Artikelnummer: | BYT-ORB1806273 |
| Hersteller Artikelnummer: | orb1806273 |
| Alternativnummer: | BYT-ORB1806273-1,BYT-ORB1806273-100 |
| Hersteller: | Biorbyt |
| Kategorie: | Antikörper |
| Applikation: | ELISA, FA, FACS, In vivo |
| Spezies Reaktivität: | Human |
| Konjugation: | Unconjugated |
| Anti-CDH6 / K-Cadherin Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa. |
| Klonalität: | Monoclonal |
| Konzentration: | Batch dependent |
| Molekulargewicht: | 144.24 kDa |
| UniProt: | P55285 |
| Puffer: | 100 mM Proline/Acetic acid 20mM Arginine pH 5.0 |
| Reinheit: | >95% |
| Target-Kategorie: | CDH6 / K-Cadherin |
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Anti-CDH6 / K-Cadherin Reference Antibody (HKT288) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%. |
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The purity of Anti-CDH6 / K-Cadherin Reference Antibody (HKT288)is more than 97.93% ,determined by SEC-HPLC. |
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Immobilized Cyno CDH6 His at 2 µg/mL can bind Anti-CDH6 / K-Cadherin Reference Antibody (HKT288),EC50=0.006944 µg/mL. |
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Human CDH6 HEK293(A6) cells were stained with Anti-CDH6 / K-Cadherin Reference Antibody (HKT288) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC71=0.08624 ug/mL. |
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The endocytosis ratio HKT288 by Hu-CDH6-HEK293(A6) increased with the increase of antibody concentration, and the Internalization Rate (%),reached 93% at antibody concentration of 2 nM. |
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HKT288 induced OVCAR3 Luciferase activity was evaluated using huCD16a(V158)-NF-AT-Jurkat Reporter Cell. The EC50 was approximately 0.6792 nM. |
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