PAKalpha/beta/gamma (phospho Thr423/402/421) rabbit pAb, Rabbit, Polyclonal

Artikelnummer: EBT-ES6462

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Artikelname:	PAKalpha/beta/gamma (phospho Thr423/402/421) rabbit pAb, Rabbit, Polyclonal
Artikelnummer:	EBT-ES6462
Hersteller Artikelnummer:	ES6462
Alternativnummer:	EBT-ES6462-50, EBT-ES6462-100
Hersteller:	ELK Biotechnology
Wirt:	Rabbit
Kategorie:	Antikörper
Applikation:	ELISA, IF, IHC, WB
Spezies Reaktivität:	Human, Mouse, Rat
Immunogen:	The antiserum was produced against synthesized peptide derived from human PAK1/2/3 around the phosphorylation site of Thr423/402/421. AA range:391-440
Alternative Synonym:	PAK1, Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK2, Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58, PAK3, OPHN3, Serine/threonine-p

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],

Klonalität:	Polyclonal
Konzentration:	1 mg/ml
Molekulargewicht:	60kD
NCBI:	5058
UniProt:	Q13153

Application Verdünnung:

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using PAK1/2/3 (Phospho-Thr423/402/421) Antibody. The picture on the right is blocked with the phospho peptide.

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