PAKalpha/beta/gamma (phospho Thr423/402/421) rabbit pAb, Rabbit, Polyclonal

Catalog Number: EBT-ES6462

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Article Name:	PAKalpha/beta/gamma (phospho Thr423/402/421) rabbit pAb, Rabbit, Polyclonal
Biozol Catalog Number:	EBT-ES6462
Supplier Catalog Number:	ES6462
Alternative Catalog Number:	EBT-ES6462-50, EBT-ES6462-100
Manufacturer:	ELK Biotechnology
Host:	Rabbit
Category:	Antikörper
Application:	ELISA, IF, IHC, WB
Species Reactivity:	Human, Mouse, Rat
Immunogen:	The antiserum was produced against synthesized peptide derived from human PAK1/2/3 around the phosphorylation site of Thr423/402/421. AA range:391-440
Alternative Names:	PAK1, Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK2, Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58, PAK3, OPHN3, Serine/threonine-p

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],

Clonality:	Polyclonal
Concentration:	1 mg/ml
Molecular Weight:	60kD
NCBI:	5058
UniProt:	Q13153

Application Dilute:

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using PAK1/2/3 (Phospho-Thr423/402/421) Antibody. The picture on the right is blocked with the phospho peptide.

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