The antiserum was produced against synthesized peptide derived from human NFATC2IP. AA range:151-200
Alternative Synonym:
NFATC2IP, NIP45, NFATC2-interacting protein, 45 kDa NF-AT-interacting protein, 45 kDa NFAT-interacting protein, Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein
function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production.,PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus.,subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.,
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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