NFATc2IP rabbit pAb, Rabbit, Polyclonal

Catalog Number: EBT-ES7785
Article Name: NFATc2IP rabbit pAb, Rabbit, Polyclonal
Biozol Catalog Number: EBT-ES7785
Supplier Catalog Number: ES7785
Alternative Catalog Number: EBT-ES7785-50, EBT-ES7785-100
Manufacturer: ELK Biotechnology
Host: Rabbit
Category: Antikörper
Application: IHC, WB
Species Reactivity: Fish, Human, Mouse, Rat
Immunogen: The antiserum was produced against synthesized peptide derived from human NFATC2IP. AA range:151-200
Alternative Names: NFATC2IP, NIP45, NFATC2-interacting protein, 45 kDa NF-AT-interacting protein, 45 kDa NFAT-interacting protein, Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein
function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production.,PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus.,subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.,
Clonality: Polyclonal
Concentration: 1 mg/ml
Molecular Weight: 48kD
NCBI: 84901
UniProt: Q8NCF5
Application Dilute: WB 1:500-2000,IHC-p 1:50-300
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).