8-Aminoadenine is an adenine receptor 1 (rAde1R) inhibitor with a Ki of 6.51 µM in rat and 0.0341 µM in human. 8-Aminoadenine inhibits isoprenaline-induced cAMP accumulation and adenine uptake in astrocytoma cells expressing rAde1R. 8-Aminoadenine serves as a lead structure for the development of adenine receptor ligands to elucidate the functions of the adenine receptor family[1].
Molekulargewicht:
150.14
Reinheit:
98.34
CAS Nummer:
[28128-33-8]
Formel:
C5H6N6
Target-Kategorie:
P2Y Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
