8-Aminoadenine is an adenine receptor 1 (rAde1R) inhibitor with a Ki of 6.51 µM in rat and 0.0341 µM in human. 8-Aminoadenine inhibits isoprenaline-induced cAMP accumulation and adenine uptake in astrocytoma cells expressing rAde1R. 8-Aminoadenine serves as a lead structure for the development of adenine receptor ligands to elucidate the functions of the adenine receptor family[1].
Molecular Weight:
150.14
Purity:
98.34
CAS Number:
[28128-33-8]
Formula:
C5H6N6
Target:
P2Y Receptor
Application Notes:
MCE Product type: Reference compound
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