VU6001966 is a brain-penetrant and selective mGlu2 receptor inhibitor. VU6001966 blocks mGlu2 receptor activity, counteracts LY379268 (HY-103558)-mediated blood-brain barrier protection and inflammatory cytokine dampening in microglia under inflammatory conditions. VU6001966 enhances antidepressant effects when combined with Scopolamine (HY-N0296). VU6001966 can be used for the research of major depressive disorder[1][2][3][4].
Molekulargewicht:
326.33
Reinheit:
99.89
CAS Nummer:
[2009052-76-8]
Formel:
C17H15FN4O2
Target-Kategorie:
Cytochrome P450,mGluR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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