VU6001966 is a brain-penetrant and selective mGlu2 receptor inhibitor. VU6001966 blocks mGlu2 receptor activity, counteracts LY379268 (HY-103558)-mediated blood-brain barrier protection and inflammatory cytokine dampening in microglia under inflammatory conditions. VU6001966 enhances antidepressant effects when combined with Scopolamine (HY-N0296). VU6001966 can be used for the research of major depressive disorder[1][2][3][4].
Molecular Weight:
326.33
Purity:
99.89
CAS Number:
[2009052-76-8]
Formula:
C17H15FN4O2
Target:
Cytochrome P450,mGluR
Application Notes:
MCE Product type: Reference compound
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