Amyloid beta Precusor Protein Antibody, Rabbit, Polyclonal
Artikelnummer:
NSJ-F51499-0.4ML
Hersteller Artikelnummer:
F51499-0.4ML
Alternativnummer:
NSJ-F51499-0.4ML
Hersteller:
NSJ Bioreagents
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, WB
Spezies Reaktivität:
Human
Immunogen:
A portion of amino acids 735-763 from the human protein was used as the immunogen for this Amyloid beta precusor protein antibody.
APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
