MD102 is a potent inhibitor of Transglutaminase 2 (IC50 ~ 0.35 µM). By inhibiting TG2 activity, MD102 modulates cancer-related signaling pathways. In cellular models, its effects are associated with p53 stabilization and downregulation of p-AKT and p-mTOR signaling, and it induces apoptosis in cancer cells.
Molekulargewicht:
389.99
CAS Nummer:
[2755794-94-4]
Formel:
C13H4BrCl2FN2O2
T86873
T86873
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
