MD102 is a potent inhibitor of Transglutaminase 2 (IC50 ~ 0.35 µM). By inhibiting TG2 activity, MD102 modulates cancer-related signaling pathways. In cellular models, its effects are associated with p53 stabilization and downregulation of p-AKT and p-mTOR signaling, and it induces apoptosis in cancer cells.
Molecular Weight:
389.99
CAS Number:
[2755794-94-4]
Formula:
C13H4BrCl2FN2O2
T86873
T86873
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