TOPOI/PARP-1-IN-1, CAS [[2948352-16-5]] Preis auf Anfrage

Artikelnummer: TGM-T87550
Artikelname: TOPOI/PARP-1-IN-1, CAS [[2948352-16-5]] Preis auf Anfrage
Artikelnummer: TGM-T87550
Hersteller Artikelnummer: T87550
Alternativnummer: TGM-T87550-10MG,TGM-T87550-50MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Compound B6, also known as TOPOI/PARP-1-IN-1, is a dual inhibitor targeting TOPOI and PARP, exhibiting low cytotoxicity and oral activity with a PARP1 IC 50 of 0.09 µM. This compound effectively inhibits cancer cell proliferation and migration, induces cell cycle arrest at the G0/G1 phase, and triggers apoptosis. In murine models, TOPOI/PARP-1-IN-1 demonstrated a tumor growth inhibition rate (TGI) of 75.4% [1].
Molekulargewicht: 718.52
CAS Nummer: [2948352-16-5]
Formel: C36H38Br2N4O2
Target-Kategorie: PARP|||Topoisomerase|||Apoptosis
T87550