TOPOI/PARP-1-IN-1, CAS [[2948352-16-5]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T87550
Supplier Catalog Number:
T87550
Alternative Catalog Number:
TGM-T87550-10MG,TGM-T87550-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Compound B6, also known as TOPOI/PARP-1-IN-1, is a dual inhibitor targeting TOPOI and PARP, exhibiting low cytotoxicity and oral activity with a PARP1 IC 50 of 0.09 µM. This compound effectively inhibits cancer cell proliferation and migration, induces cell cycle arrest at the G0/G1 phase, and triggers apoptosis. In murine models, TOPOI/PARP-1-IN-1 demonstrated a tumor growth inhibition rate (TGI) of 75.4% [1].
Molecular Weight:
718.52
CAS Number:
[2948352-16-5]
Formula:
C36H38Br2N4O2
Target:
PARP|||Topoisomerase|||Apoptosis
T87550
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