Synthesized peptide derived from human FA8A (light chain, Cleaved-Glu1668)
Alternative Names:
Coagulation factor VIII (Antihemophilic factor, AHF, Procoagulant component) [Cleaved into: Factor VIIIa heavy chain, 200 kDa isoform, Factor VIIIa heavy chain, 92 kDa isoform, Factor VIII B chain, Factor VIIIa light chain]
disease:Defects in F8 are the cause of hemophilia A (HEMA) [MIM:306700]. HEMA is a common recessive X-linked coagulation disorder. The frequency of hemophilia A is 1-2 in 10,000 male births in all ethnic groups. About 50% of patients have severe hemophil
