MAK683 is a potent and selective small molecule inhibitor of the Embryonic Ectoderm Development (EED) protein, with IC50 values ranging from 26 to 89 nM across multiple biochemical assays. This inhibitor is a valuable chemical probe for investigating the role of EED and PRC2 complex function in epigenetic regulation, cancer biology, and stem cell research, both in vitro and in vivo.
Molecular Weight:
376.39
Purity:
99.92% (May vary between batches)
CAS Number:
[1951408-58-4]
Formula:
C20H17FN6O
Target:
Histone Methyltransferase
Application Notes:
Solubility: DMSO:4.33 mg/mL (11.5 mM)
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