CD163 (Hemoglobin/Haptoglobin Complex Receptor, M130 antigen, Ber-Mac3, Ki-M8, SM4) (Biotin), IgG1, Clone: [9i228], Mouse, Monoclonal
Catalog Number:
USB-C2548-90C
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| Article Name: | CD163 (Hemoglobin/Haptoglobin Complex Receptor, M130 antigen, Ber-Mac3, Ki-M8, SM4) (Biotin), IgG1, Clone: [9i228], Mouse, Monoclonal |
| Biozol Catalog Number: | USB-C2548-90C |
| Supplier Catalog Number: | C2548-90C |
| Alternative Catalog Number: | USB-C2548-90C-250 |
| Manufacturer: | US Biological |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | ELISA |
| Immunogen: | Recombinant corresponding to amino acids Gly41-Ser1045 from human CD163 expressed in NS0 cells. Species Sequence Homology: mouse, 74%, rat, 75%, bovine, 84%, equine, 86%, porcine, 86%, and canine, 87%. |
| CD163, also known as hemoglobin scavenger receptor, is a type I transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region. Two alternatively spliced cytoplasmic variants of human CD163 exist. A soluble form of CD163 can also be released by metalloproteinase-mediated shedding of the extracellular domain. CD163 mediates the endocytosis of haptoglobin-hemoglobin complexes. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA (detection): 0.5-2ug/ml Optimal dilutions to be determined by the researcher. Recommended Pair: Detection: C2548-90C Capture: C2548-89G2 Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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